Laboratory staff monitored all requests for Q fever serologic testing from general practitioners and hospital clinicians to identify any additional cases that might be linked with the outbreak.
Cases were identified by means of a rapid identification system at area hospitals, and the Warsaw Cancer Registry was used to identify any additional cases that were missed by the rapid identification system.
However, the Poisson-Fitter rejected a few additional cases that were identified as transmissions of a single viral variant by phylogenetic and distance analyses: 3 in gag (subjects E, F, and QI) and 3 in env (subjects C, OU, and QI).
It contributes to the detection of a few additional cases that were not detected by the other 2 surveillance systems.
Typically a series of outbreaks or events is calculated according to an epidemic model, and case counts are added to the real data to simulate the additional cases that would occur as a result of the outbreak.
A substantial genetic screening effort, carried out on an enlarged number of patients, would be necessary for the identification of additional cases that may be related to the haploinsufficiency of DG.
In the TMA analysis, we also detected three additional cases that exhibited between one and four cells containing a locus-specific AR-gene amplification (see example in Supplementary Figure 1).
The agency said it had asked Pfizer for information on additional cases that might be similar.
But one would be hard pressed, I think, to find additional cases that fit the mold.
Yesterday, Mr. Levy said a review of 129 sexual misconduct cases handled in the last three years by Elaine Smith, the Board of Education investigator who oversaw the 1998 inquiry on Mr. McFarlane, found six additional cases that required follow-up by the Police Department.
