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DNKv4 neurons display shortened latency to firing, a lower threshold for repetitive firing, and a progressive decrement in AP amplitude to an adapted state.
DNKv4 neurons displayed a dramatically shortened delay to the first action potential (AP), a lower threshold for inducing repetitive firing, a higher initial firing frequency, and then a progressive decrement in AP amplitude to an adapted state.
Without Kv4 channel function, firing frequency was increased, but AP amplitudes progressively decreased during the stimulus as shown in Figure 6D, reaching an adapted state especially with large current injections (Figure 6C D).
However, in such cases, an adapted state is generally maintained only for several generations.
Within the oddball sequence, after the presentation of the deviant tone, SSA takes several repeats of the standard tone to reach an adapted state (Ulanovsky et al., 2004).
The transition from unadapted to an adapted state for the N'Dama, Adaptaur, Senepol and Criollo could also involve elements of phenotypic plasticity, defined as the ability of a genotype to produce more than one phenotype in response to differing environments (Scheiner 1993; de Jong 2005; Fordyce 2006).
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John Charles, chief of the programme's International Science Office, said data from six-month spells in space did not suggest that the human body adjusts to a new adapted state over that period of time.
Each symbol represents a different combination of incubation temperature and adapted state (parental, 16 °C-adapted, and 28 °C-adapted).
The independent variables were adapted state (parental, 16 °C-adapted, and 28 °C-adapted) and strain origin (AK, MT, and NV), with strain origin nested within adapted state.
To analyze the performance of the cell in its adapted state, we then started an adaptation phase by rotating the first image by 360° to the right within 2.4 s, which corresponds to an angular velocity of 150°/s.
The time constant of adaptation was used to delineate a period corresponding to the adapted state for the analysis of orientation selectivity with constant contrast conditions: adaptation was considered to have reached a steady state at a time corresponding to three times the time constant of adaptation.
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