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In this paper we propose an active replication scheme in which data consistency can be maintained.
In [20], recovery is reached using an active replication technique, where a controller manages a priority list through Backup-ID from resources.
The replicon system enables cell-culture compound efficacy evaluation against an active replication complex, and a functional replicon dependent upon a genotype 2b polymerase would augment existing cell-culture efficacy studies that are presently limited to genotype 1a, 1b, and 2a replicons.
During the acute phase of infection, an active replication of HDV is observed whilst HBV replication is partially suppressed.
Further whole genome investigation, coupled with studies on individual DNA molecules, will be useful to identify DNA elements and their associated chromatin features including, epigenetic modifications, participation in higher order structures, and function in regulating gene expression which enhance the likelihood of forming an active replication initiation complex.
In contrast, the level of PCNA2 transcripts representing the status of an active replication of nuclei DNA was significantly low in dwf7-1.
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Interestingly, an Haloferax volcanii strain lacking all active replication origins was constructed, and the recombination-dependent manner of chromosome replication was proposed to be used (Hawkins et al. 2013; Michel and Bernander 2014).
Chromosome breakage in unperturbed wild-type cells occurs mostly in the sensitive S-phase of the cell cycle (Lisby et al. 2001), with an open chromatin and active replication forks that represent a potential internal source of DNA breaks and genome instability.
We identified a list of 252 active replication origins in L. kluyveri and found a considerable divergence in origin location with S. cerevisiae and L. waltii as only approximately 25% of active origins were conserved between the three genomes.
This suggests that a >95% loss of MCM2-7 does not produce a comparable reduction in active replication forks.
Here, we provide a list of 252 chromosomally active replication origins and found a highly significant association between these origins and the set of previously published ARS.
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