Another challenge when designing an fMRI study on ASDs is the widely acknowledged difficulty of recruiting a homogeneous group of patients.
Most of its 25 members are Shiites; all have said they are bound by the ayatollah's opinion, despite the acknowledged difficulty of holding elections without a national census and with the country under occupation.
The Quadratic Assignment Problem (QAP) has attracted considerable research efforts due to its importance for a number of real life problems, in addition to its acknowledged difficulty.
Other diagnostic guidelines are more stringent, but also are more difficult to use in practice due to the acknowledged difficulty in obtaining ocular samples for testing [10, 19].
This observation would be consistent with an underlying publication bias towards underreporting of negative results, which seems plausible in view of the widely acknowledged difficulty of accurately generating positive B-cell epitope predictions [ 20, 54].
Despite the widely acknowledged difficulty in accessing health services in regional areas, rural women in this study did not consider that these difficulties influenced their decisions to use CAM.
Because of the acknowledged difficulty in growing myelinated CNS tissue, one long-standing method of generating myelinated CNS axons has been by sourcing tissue from both the peripheral nervous system and CNS and combining them in co-culture (Wood & Bunge, 1986).
If it is capable of successful development by an energetic race which has, what we lack, the incentive to cope with acknowledged difficulties in order to win a new home free from restrictions and persecution… they should be allowed to do so". .
In spite of the acknowledged difficulties, there was strong endorsement for building a system of review that would support a collaborative approach to research.
Among the phyla that yielded successful COI sequences, echinoderms and flatworms (Platyhelminthes) have long been receiving particular attention in DNA barcoding and related studies due to acknowledged difficulties in obtaining quality sequences.
