The phrase "an abnormal buildup of" is correct and usable in written English.
It can be used in contexts where you are describing an unusual accumulation of a substance or condition, often in medical or scientific discussions.
Example: "The doctor explained that the patient was experiencing an abnormal buildup of cholesterol in their arteries."
Alternatives: "an unusual accumulation of" or "an excessive gathering of".
She was born prematurely and soon received a diagnosis of hydrocephalus, an abnormal buildup of fluid on the brain.
Inherited forms of both diseases have been traced to gene mutations associated with an abnormal buildup of the RNA-binding protein, TDP-43, in the brain.
What can I do? A. Dupuytren's contracture is a disorder that develops when the palmar fascia — the tissue between the skin and tendons in the palm — thickens and contracts due to an abnormal buildup of collagen, causing one or more fingers (usually the little and ring fingers) to bend inward.
HAPE is a noncardiogenic form of pulmonary edema that is characterized by smooth muscle proliferation and exaggerated hypoxic pulmonary vasoconstriction, leading to an abnormal buildup of fluid in the lungs and vascular leakage through overperfusion, stress failure, or both.
For each of these nsSNVs, we extracted the type of change and their associated drug efficacy (the ability of a drug to produce a desired effect) and toxicity (abnormal buildup of prescription medication in the bloodstream).
ADA deficiency results in the abnormal buildup of this toxic product, which is particularly lethal for white blood cells.
When cells from children with the condition are exposed to the drug in lab dishes, they eliminate their abnormal buildup of progerin and survive longer, Collins, Kan Cao of the National Human Genome Research Institute, and colleagues report today in Science Translational Medicine.
The mutation leads to the buildup of an abnormal version of the protein, which causes misshapen nuclei and other changes within cells.
Hutchinson-Gilford progeria is caused by a spontaneous mutation during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their cells that, among other changes, distorts the nucleus and alters gene expression.
Characterized by an abnormal increase of food consumption.
