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Not only was it possible to amplify up to 444 bp of mtDNA, we also successfully amplified a number of high molecular weight alleles from the nuclear STRs tested (under ∼375 bp for autosomal markers and under ∼335 bp for the Y-chromosomal markers).
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From these preparations, we conducted standard PCR to amplify a number of products.
Their views have been amplified in a number of alarming articles in the press, and have set off a fierce debate that rages in scientific journals and conferences around the world.
"We believe the recent Bitcoin milestone has been driven primarily by institutional money which is finally mobilizing, and organic consumer demand which has been amplified by a number of direct sales initiatives around the world," he stated.
Subsequently, the human MTDH gene was localized at chromosome 8q22 and has been reported to be amplified in a number of malignancies such as malignant glioma [6], hepatocellular carcinoma (HCC [7], and breast cancer [8], [9], [10].
However, TSPAN31 was also found highly amplified in a number of GBM patients elsewhere.
There is also good evidence that FGFR1 and FGFR4 are amplified in a number of breast tumours.
Similarly the MYC oncogene is amplified in a number of pathologies, particularly in neuroblastoma where MYC-N amplification is a diagnostic marker [ 10].
This kinase is also known to be amplified in a number of human cancers and tumour cell lines (Jeng et al, 2004).
Genetic variation or extracellular signals that affect any part of the feedback cycle would tend to be amplified over a number of cycles, potentially leading to a growing imbalance in the system over time.
The authors found that the Pak4 gene localizes at a region of chromosome 19 that is commonly amplified in a number of human pancreatic tumors, colon tumors, and ovarian tumors [ 19].
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