Sentence examples for amplification influence from inspiring English sources

HER2 gene amplification in those cancers considered HER2+ is variable and raises the question does the degree of HER2 amplification influence outcome?

These second rounds of amplification influenced the gene expression profiles.

In the neoadjuvant setting, Guiu et al (2010) demonstrated that the level of HER2 gene amplification influenced the pathological complete response rate (pCR), with high amplified cancers (>10.0 HER2 gene copies per cell) showing a significantly improved pCR rate, although this did not translate into a RFS or OS benefit.

The hypervariable region chosen for amplification can influence the PCR-DGGE profiles.

The hypervariable region(s) chosen for amplification can influence the PCR-DGGE profiles and diversity indices produced from community DNA samples, and even subtle differences in primer sequences can result in substantially different profiles and downstream assessments of microbial diversity.

We studied how differential allele amplification efficiencies influence the confidence level of genotypes and proposed, accordingly, a new way of estimating the minimum number of sequences per individual required for reliable genotyping.

When a background flora was present at concentrations≥106 (CFU/ml), the DNA amplification was influenced and a change in the log linear slope leading to a lower amplification efficiency was observed.

For some DNA samples, particularly those from hair follicles, success in amplification was influenced by the type of Taq polymerase used.

The level of HER-2 gene amplification significantly influenced pCR but not RFS or OS in non-metastatic breast cancer treated with trastuzumab-based neoadjuvant therapy.

We analysed whether the level of human epidermal growth factor receptor-2 (HER-2) amplification significantly influenced either pathological complete response (pCR) or recurrence-free survival (RFS) and overall survival (OS) after trastuzumab-based neoadjuvant therapy.

We were also interested to see if SELEX amplification steps also influence the base composition.