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With respect to achieving selectivity for APHs vs. ePKs, the three kinase-CKI-7 structures reveal ample differences in binding, as also reflected in the variance in the enzymes' Ki values, to confidently suggest that inhibitors based on the isoquinoline scaffold can be developed for either APH(3' -IIIa or APH(9)-Ia that do not bind to CK1 and likely other ePKs.
If this comparison shows ample differences in the resulting images, then TIC is not recommended.
However, also ample differences between aging on a chronological and a pathological scale were apparent.
It is probably not expected that they and/or their genetic control have anything in common, and the study finds ample differences.
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The ample difference in the number of revamps between the latest iTrend and your local joint's ping pong table is as much a sign of the times as it is of market opportunism, but also a consequence of the old world philosophy that some things are best left unchanged.
Consistent with these sex differences, ample evidence has now been accumulated that the dominant male grows faster than similar sized subordinate males and that the highest ranking subordinate male shows strategic adjustments in growth to ensure a safe-size difference with the dominant male and potentially prevent conflict [50] and eviction [15], [45], [51].
Show and tell consumers what makes your brand different and provide ample evidence that this difference is something they really care about.
It is possible that there has not been ample time for distinct differences in performance between lightweight and normalweight concrete decks included in this study to become evident during field observations.
It is possible that that there has not been ample time for distinct differences in performance between lightweight and normalweight concrete decks included in this study to become evident during field observations.
Although we have found ample evidence for allelic differences in splicing, isoforms that result entirely from sequence variants might be less common.
The varying rates of karyotypic change predicted for morphologically divergent lineages, coupled with their ample set of biological differences, depict a scenario in which highly rearranged karyotypes might have been established by different means in species with distinct life histories.
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