After idealizing the side-chain structures, the free energy is either improved by a relatively biger amount or worsened by a relatively smaller amount as shown in Figure 7. Unfortunately, in most cases, the free energy is worsened slightly but is still in a stable state with negative values.
For example, based on the Overall Treatment Effect (OTE) scale [ 18], patients can be assigned into groups representing no change (i.e., remaining stable), small improvements, moderate improvements or large improvements, and small amount of worsening, moderate worsening, or large amounts of worsening.
The current shortage worsened when the amount of power expected to be imported from the Northwest was cut by a third on Wednesday because the power was needed in Washington and Oregon, which were experiencing cold weather.
In this study, we were unable to show that the discrepancy between BD and serum lactate worsened with the amount of volume resuscitation or the duration of the case.
Although adult epidemiological studies associate light to moderate ethanol consumption with improved insulin sensitivity and wine consumption with reduced cardiovascular risk, other cross-sectional and prospective studies implicate a dose-dependent effect of alcohol in metabolic syndrome, and suggest that chronic consumption of large amounts of ethanol worsen insulin sensitivity.
Over the past two weeks, the animal's condition had worsened significantly, losing significant amounts of weight as she stopped eating.
This relation has worsened significantly in the last years, amounting to 1 79 in 2013 [31].
Froome claimed that while he had increased the dosage when his asthma worsened, he had not surpassed the allowable amount.
Since then, drought conditions have worsened and environmental rules have restricted the amount of water that can flow from Northern California.
The railroad president, David L. Gunn, said in a letter to senators on Wednesday that the $1.34 billion "leaves us at great risk in terms of reliability" but that Amtrak could continue operating with an appropriation of that size "and hopefully not worsen the amount of deferred maintenance".
