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The phrase "amount to a significant" is correct and usable in written English.
It can be used when discussing the extent or degree of something, often in relation to its importance or impact.
Example: "The changes in policy may amount to a significant improvement in employee satisfaction."
Alternatives: "constitute a considerable" or "represent a notable".
Exact(52)
"Over the years, this can amount to a significant amount of money," Mr. Block said.
The changes also amount to a significant reduction in benefits for single parents.
This, in itself, would amount to a significant hit to creditors.
But even a relatively small reduction in the interest rate can amount to a significant savings.
time is probably small enough that it wouldn't amount to a significant quantity of money for most people," he said.
The downside is that this would amount to a significant reduction in the "replacement rate" of Social Security benefits.
Similar(8)
That description amounts to a significant shift.
For Trump, the surprising turn of events amounted to a significant diplomatic setback.
Its annual output of coal amounts to a significant portion of the total for the province.
That amounts to a significant problem, even in a country with a national budget of about $600 billion.
"And this amounts to a significant, but hidden, 'unbalancing' of the economy.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com