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The amount of wake effect is minimized, if: ① the WT12 is placed with an angle θ1 with respect to WT11; ② the WT13 is placed with an angle θ2 and greater than that with respect to WT11.
While many (28) QTL affected a particular sleep-wake trait (e.g., amount of wake) across the full 24-hr day, other loci only affected a trait in the light or dark period while some loci had opposite effects on the trait during the light vs. dark.
For example, the network analyses revealed a novel chain of causal relationships between the chromosome 17@29cM QTL, total amount of wake, and duration of wake bouts in both light and dark periods that implies a mechanism whereby overall sleep need, mediated by this locus, in turn determines the length of each wake bout.
"Webster's rules" improve the specificity of scoring of out-of-bed sleep and the accuracy of 24-hour sleep scoring at the expense of over-estimating the amount of wake within sleep.
PSG sleep examination gave further support to a CNS-activating effect of duloxetine as both the 60- and 120-mg dose reduced total sleep time, increased the amount of wake, increased time to fall asleep, and substantially disrupted REM sleep.
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"Wake after sleep onset" (WASO) was the amount of waking minutes within total sleep time.
One suspects he's going to be doing a fair amount of waking up and wondering over the coming years.
The increased amount of waking in adolescent rats agrees with the commonly reported age-related changes in sleep quantity [51].
It is intriguing that the increased locomotor intensity, during the dark period and the very beginning of light period, did not continue during the remaining light period although a substantial amount of waking time still occurred.
A substantial amount of waking hours was spent in different types of sedentary behaviours on workdays and non-workdays.
Sleep over the last 4 weeks was assessed using 12 questions relating to the time taken to fall asleep, quality of sleep, amount of waking during the night, and the effect of sleep on daytime functioning.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com