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Splashing the compounds into neuronal cultures, the team found that a common class of antibiotics that includes penicillin increased the amount of transporter that healthy cells use to reabsorb glutamate by up to 3 times.
The absolute amount of transporter protein in mouse brain capillary endothelial cells was determined by mass spectrometric analysis [ 26].
No fluorescence decay was observed in the absence of transporter, and the rate of decay was clearly dependent on the amount of transporter 1 added.
Despite no major effect on CFTR, we observed a numerical decrease of SGLT-1 expression that could be reflective of a higher Na+ reabsorption mediated by an higher amount of transporter by a negative feedback regulation mechanism.
A possible explanation is that on the luminal side of renal tubules, URAT1 is involved specifically in uric acid reabsorption and consequently the amount of transporter protein is less than OAT1-4 that participates in the metabolites of diverse compounds.
The lack of change of Mrp2 content in mixed plasma membranes in response to ANIT may be tentatively explained by the fact that intracellular accumulation of Mrp2 in enriched microsomal membranes represents a small fraction of the total amount of transporter in the cell according to previous report [ 20].
Similar(54)
The large amount of transporters can be linked to the secretion and transport function of glandular trichomes.
This technology can be used to engineer advanced phytoremediators, increasing their ability to pump heavy metals into a safe compartment while requiring only a small amount of transporters rather than a large amount of chelating peptide material.
This is twice the amount of transporters compared to the low concentration of phenanthrene exposure.
Therefore, the level of reduction by dithionite is expected to be dependent on the amount of transporters in the vesicle preparations, and the addition of more FtsW should result in fewer transporter-less LUVs.
The result was different when large amounts of transporter were in the membrane due to co-expression of collectrin.
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