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The large amount of inactive ligand structures are usually taken from organic molecule data banks like ZINC [2].
It is excreted in urine and bile mainly as unchanged drug and a small amount of inactive metabolites with a terminal elimination half-life of about 9 h (Husain et al. 2011).
In order to reduce the amount of inactive materials, such as binders and carbon additives in battery electrode, porous cobalt monoxide nanofibers were directly grown on conductive substrate as a binder/additive-free lithium-ion battery anode.
Analysis by synthesizing the characterization results and catalytic activity data shows that large amounts of adsorbed oxygen, small amount of inactive compounds on the surface and low NO2 desorption temperature are favorable for the oxidation of NO.
The results indicate that an excess amount of inactive RNR does not affect the distribution of SeqA foci significantly.
CEUS was used to assess the amount of inactive and active tenosynovitis.
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Many numerical models evaluate turbulent mixing using turbulent kinetic energy k, which may contain significant amounts of inactive turbulence (e.g., in real or simulated atmospheric boundary layers).
The modulatory effect of C. albicans on IL-1β expression was confirmed by the fact that increased amounts of inactive IL-1β (33 kDa) were detected early during the infection which then dropped dramatically.
In silico analyses are increasingly being used to support mode-of-action investigations; however many such approaches do not utilise the large amounts of inactive data held in chemogenomic repositories.
The fact that SD is positively correlated with tumour grade in glioma but negatively with grade in breast cancer could reflect differential highlighting of dark or bright regions in these tumour types, perhaps reflecting varying amounts of inactive fibrosis.
The active fraction of PTX (X, bound to tubulin), was calculated as the difference between the initial amount (A) and the total of inactive drug (B, C, D) [X = A - (B + C + D)].
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