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Second, we demonstrate that even with a little amount of annotation, a good performance for annotation suggestion can be reached, resulting in a substantial annotation speedup.
These annotations were used to increase the amount of annotation for our gene set, as there are insufficient annotations in E. coli that have been experimentally identified.
There is already evidence that causative SNPs for a wide range of traits are enriched for certain functional categories [7] [8] and an increasing amount of annotation is available that could be used for such studies.
We have shown that the amount of annotation is very sparse with around 4% of the studies having keywords corresponding to all the steps relevant to the protocols.
The verification of array results was based on their level of differential expression and the amount of annotation available for their corresponding BmiGI V2 sequence.
This approach takes advantage of the large amount of annotation of the transcriptome and can be used on other arrays with genome-wide coverage.
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In the following, we do not compare with such methods since confidence scores require a substantial amount of annotations to be trustworthy.
As the volume of biological data has grown, so has the amount of annotations available (3).
Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years.
The songs receive just the right amount of biographical annotation, with Ms. Mitchell's "Cactus Tree and Mr. Cohenn's "Bird on a Wire" cited as definitive expressions of who they were at the time, both in their own ways consumed by desire.
In a data system such as PubChem, with a very uneven amount of biological annotation, it is helpful to find related chemical structures where more information is known.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com