Effect of independent variables (oil amount, lecithin amount and glycerol amount) toward response variables (particle size, polydispersity index, zeta potential and osmolality) were studied using central composite design (CCD).
Several operating parameters (MeCN/acetic acid ratio in the extraction solution (i.e., acetic acid percentage), water volume, extraction time, PSA amount, C18 amount, and GCB amount) were investigated using a Plackett Burman (P B) screening design.
Results were reported as low amount, moderate amount, and high amount depending on intensity of colour formation [ 27].
Health care costs were calculated as the sum of the following elements: amount paid by insurance, copay amount, coinsurance amount, deductible amount, and secondary insurance amount.
The amount of sodium alginate, amount of calcium Chloride, and amount of magnesium stearate were selected as formulation variables.
Critical process parameters namely: polymer type and amount, drug amount and internal aqueous phase volume ratio were evaluated for their effect on entrapment efficiency (EE%) of RS.
The independent variables employed were amount of pectin and amount of starch paste, each at three levels.
These values were 3.8, 3.1 and 3.3 mg, for pH of solution, amount of nanoparticles and amount of extractant, respectively.
Amount of granulating fluid and amount of binder were selected as formulation variables and spheronization speed as a process variable.
Seven out of eight included studies reported on both the amount of anchorage loss and amount of incisor retraction.
