Sentence examples for among the alterations from inspiring English sources

Another patient (case #6) with a biopsy 31 months prior to treatment had only a BRAF mutation among the alterations of known significance.

Among the alterations affecting cell growth and differentiation mechanisms, a key pathogenetic role was demonstrated for NOTCH1-activating mutation, detectable in about 60% of the cases, with or without associated FBXW7 gene inactivation.

Among the alterations we observed in the immortalized vHMEC-ras0.5 cells were an upregulation in telomerase activity as well as DNA methylation at several gene loci, including the RASSF1A, SFRP1, p57, and MGMT gene loci.

Among the alterations more recurrently found in BRCA1 tumours compared with sporadic cases were losses at 4q32.3-q34.1, 6q22.33-q26 or 12q21.2-q23.2 while gains at 6p12-p11, 10p14-p11 and 10q22 were found to be more frequent in BRCAX tumours (compared with BRCA1 cases; Figure 1A and IV).

Second, we were able to demonstrate that such heterogeneous variation in effect sizes for the latter relationship could be mediated by the among-year alterations in the studied demographic factors determining the level of competition for breeding opportunities and age composition of the population.

We investigated four potential socio-ecological factors, and found evidence that the among-year alterations in the demographic structure of the population (density, age composition) can be responsible for the heterogeneous effect sizes.

Taking into consideration that breast cancer is one of the leading causes of cancer related deaths among women, exploring the alterations of ECM of mammary gland and the role in tumour processes is of central importance in cancer biology.

Among all of the alterations elicited by feruloyl amide treatment, the most striking one was a rapid and sustained increase (>50-fold at 10 min after treatment [ Fig. 1D]) in the level of 5-phosphoribosyl-1-pyrophosphate (PRPP).

Among the genetic alterations identified, two regions of recurrent amplification emerged.

Among the trinucleotide alterations, XpCpG → XpApG was detected in 13/14 patients.

Among the hearing alterations, 50% presented occupational NIHL whereas 41% were in the early stage of occupational NIHL [ 8].