Among Japanese, flavonoid and isoflavone intake is the main component among nonnutrient phytochemicals with antioxidant potential in the diet.
Among these phytochemicals, dietary flavonoids are an important and common chemical class of bioactive products, found in several fruits and vegetables.
Moreover, the content variation was more than 1500 times among these phytochemicals.
In this study, we show antagonistic relationship among two phytochemicals (alkaloids and saponins), an observation that can only be obvious when the compounds are fractionated and tested separately.
Zerumbone was more effective in attenuating the effect of TCDD among all phytochemicals compared, but auraptene affected that of DDT with greater potency.
Among these phytochemicals present in plant-derived foods, polyphenols have gained much interest due to their diverse potential beneficial effects in human health.
Recently, phenolic compounds have received increasing significance among various phytochemicals, due to their wide distribution in the plant kingdom and for their biological activities, namely, anticarcinogenic, antiatherogenic, anti-inflammatory, antimicrobial, and antioxidant activities [ 7– 9].
Among these phytochemicals, three diterpene lactones consisting of andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG) possess the highest bioactivity in treating the hardly curable diseases [ 17, 18].
Among the phytochemicals that accumulate in Echinacea [ 2, 3], four major classes, polyunsaturated alkamides/ketones, caffeic acid derivatives, glycoproteins, and polysaccharides, exhibit biological effects in vitro and in vivo.
