Sentence examples for amendments of the protocol from inspiring English sources

YMK is the medical monitor for the study; he has led amendments of the protocol, reviewed the data, and led the development of the clinical study report.

The MREC, will be informed of amendments to the protocol or patient information.

Suppression of dose level 6 and 7 after amendment of the protocol.

However, the results of the IES trial led to the amendment of the protocol and all patients on tamoxifen switched to examestane.

In the 48 couples who received in vitro fertilisation with single embryo transfer before the amendment of the protocol, 22 (46%) women had a healthy singleton child and three (6%) women had healthy twins.

In the 153 couples who received strict in vitro fertilisation with single embryo transfer after the amendment of the protocol, 82 (54%) women had a healthy singleton and four (3%) women had twins.

Following amendment of the protocol, eligible patients in Cohort 2 were required to have cutaneous disease at study entry, were stratified by prior trastuzumab therapy versus no prior trastuzumab therapy, and were randomized in a 5 5 2 ratio to receive daily monotherapy lapatinib 1,500 mg, lapatinib 1,000 mg + pazopanib 400 mg, or monotherapy pazopanib 800 mg, respectively.

Upon reviewing the report, the DSMB expressed satisfaction with the findings and recommended continuation of recruitment with no amendments to the protocol.

Amendments to the protocol are changes of a legal document which has a binding value and therefore must be approved in writing and signed in two copies by the same signatories of the protocol.

Small amendments to the protocol, concerning the methods of recruitment and the PROMs used, have also subsequently been approved and are included in this paper.

All minor and major amendments to the protocol will be approved by the REC, and participating general practices will be notified of any protocol amendments relevant to them.