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Therefore, 45 miRNAs were amenable to validation testing.
One source is the inherent limitation of questionnaire information, such as subjective symptoms and self-reported diagnoses, which are generally not amenable to validation.
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Hence, a prioritization approach such as ToxPi, when implemented in the broadest sense, incorporates both objective chemical and biological data that are amenable to external validation, and other considerations such as use and exposure that can be validated only in terms of a predefined subjective framework.
However, the proposal that the two experiments would give the same result is amenable to experimental validation, and as discussed elsewhere in this paper, there is a backup option in case the proposed equivalence fails validation.
"Our model is not amenable to formal validation," says the Harvard group in its main report, "because there are no controlled experiments in which the introduction and consequences of B.S.E.
The model leads to numbers that fit well the limited clinical data available on humans and makes predictions which, besides being amenable to experimental validation, may provide further insight into the understanding of a variety of hematopoietic disorders.
Direct microscopic detection of protozoal pathogens requires significant expertise and is not readily amenable to downstream validation.
Although virus metagenomics cannot provide direct data on the structure and functionality of the discovered viruses, through genome analysis, it yields a wealth of predictions that are amenable to experimental validation.
Essentially, the genomic and genic SSR and SNP markers developed especially by Indian initiatives are amenable to large-scale validation and high-throughput genotyping at the whole genome level.
Together, these results achieve a comprehensive molecular identification of key elements of the substrate translocation pathway and the underlying allosteric mechanism in DAT, at a level of detail that is directly amenable to further experimental validation.
While it is possible that a uORF of less than 20 codons could encode a functional peptide, ORFs longer than this are potentially easier to identify as conserved between species and furthermore would be more amenable to subsequent experimental validation.
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