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We start by showing that the connectivity controller is invariant under the action of the special Euclidean group SE(3) and therefore is amenable to reduction of the dynamics by this action.
To establish disulfide connectivity, we used partial reduction by TCEP (Materials and Methods), and the protocol is outlined in Fig. 6 A. Our working assumption was that the surface-location of the presumed C2 24 disulfide bond would make it more amenable to reduction compared to the buried C21 96 disulfide bond.
The catalytic cysteine thiol is first oxidized to the sulfenic (-SOH) form, which is amenable to reduction by cellular enzymatic mechanisms or with reducing agents in vitro, followed by further sequential steps of oxidation, to sulfinic (-SO2H) and sulfonic (-SO3H) forms, leading to irreversible PTPase inactivation.
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Few hospital-acquired diagnoses are preventable in every case, but most have been shown to be amenable to a reduction in their rates.
Grade 3 adverse event amenable to dose reduction was recorded in two patients, consisting of neutropenia and anaemia combined with neutropenia, respectively.
In this exploratory categorisation, a large minority of emergency readmissions (eg, those that are potentially preventable or due to data artefacts) fell into groups potentially amenable to immediate reduction.
The complex dynamic of care that occurs when providing service in the home may not be as easily amenable to risk reduction as care in more controlled care environments, such as hospitals.
A Delphi panel of physicians, nurses, and allied health care providers selected items readily measurable, identifiable on admission, thought to have a relatively high likelihood of an association with adverse health outcomes and be potentially amenable to risk reduction strategies [ 1, 15].
Estimates of how LOS varies between providers after allowing for differences in case-mix can also provide measures of the extent to which LOS may be amenable to potential reductions by high cost providers in response to the introduction of a prospective payment system.
The inclusion criteria were distal forearm fractures that were closed (simple), not intra-articular, non-comminuted and considered by the attending emergency specialist to be amenable to manipulation and reduction within the department.
Theoretical treatment of CTBT activity revealed that this compound might be amenable to one electron reduction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com