Protein arrays might overcome both shortcomings, as structural epitopes are amenable to display, and, if processed correctly, may also take post-translational modification into account.
The scFv, which is known for its lower thermodynamic stability [ 31] tends not to prematurely fold in the cytosol of bacteria and is amenable to display and localisation to the periplasm regardless of whether a post or co-translational translocation approach is used [ 30, 32].
What we identify as an audible wheeze, rhonchus, or crackle – signs that often prompt us to initiate or modify treatments – possess acoustic 'frequency signatures' amenable to categorization, quantification, and display [ 2].
In designing the targeting strategy for these proof-of-concept experiments, we selected a clinically approved graft that is 1) in wide use for both full-thickness burns and chronic wounds, 2) a biosynthetic formulation that is stable at room temperature, 3) suitable for combinatorial screening and 4) amenable to biopanning using phage display.
Importantly, the possibility to generate these macrocyclic peptides in protein-fused or isolated form make the present methodologies directly amenable to integration with well-established display platforms (e.g., phage or mRNA display) or intracellular selection systems, respectively, for library screening.
Reporting imaging studies in a structured way is certainly feasible, as the information in radiology reports is just as amenable to computer-based storage, processing, and displaying as pixels, voxels and images [7].
The major germline constituents of the scFv VH and VL domains were determined (Table 1) in order to evaluate whether particular germline sequences are more amenable to expression in E. coli and hence display on phage.
Furthermore, we demonstrate that this 2G12 (Fab)2 display system is amenable to selection of functional clones using a mock selection.
I would venture to affirm, that if even the more advanced and more formidable symptoms be displayed, still the case may be amenable to the influence of rest, and this I hope to prove by illustrative cases.
Vesicular breath sounds, wheezes, rhonchi, and crackles possess acoustic 'signatures' amenable to detection, quantification, and moment-by-moment visual display.
Fractal objects display large scale-disparity and complexity while being amenable to a simple and standardized description.
