Sentence examples for amenable target from inspiring English sources

This suggested that they may represent an amenable target for electron and X-ray crystallographic studies in much the same way that bacteriorhodopsin has.

The loss of exon 16 does not disrupt the reading frame, and has been reported to not even raise serum CK levels, indicating this should be a highly amenable target for exon skipping.

In contrast, the slower progression of white matter damage suggests it is a more amenable target for therapeutic intervention in the first few days after injury.

We further conclude that upregulation of GRP78 allows specifically quiescent tumor cells to survive for prolonged periods and this may be an amenable target to kill residual MM cells.

103, 104 Although the donor splice site proved to be a most amenable target for exon 23 skipping, the acceptor site was unresponsive, indicating a limitation to directing AOs to obvious splice motifs.

Because kinase-inactive HER3 is not presently an amenable target for forthcoming HER TKIs, molecular approaches that can efficiently block heregulin-triggered HER3 transactivation or nucleocytoplasmic trafficking of heregulin might offer novel strategies with which to manage HER-driven breast cancer disease.

Diet and lifestyle factors associate with incidence of hypertension in Thais and may be amenable targets for hypertension control programmes.

Additionally, mutations found in cancer cells that weaken IRE1α RNase activity may be amenable targets for allosteric modulation.

Given that the activity of TLR7 and 8 can be modulated by small synthetic agents such as mianserin, these receptors may provide amenable targets for the development of new therapeutics for RA.

NG2 may be an amenable therapeutic target worth exploring for GBM patients.

The discovery of these endogenous molecules that exclusively inhibit metastasis and the understanding of their actions suggest that metastasis is an amenable therapeutic target.