Sentence examples for amenable lead from inspiring English sources
We anticipate that a large chemical library screen currently underway that employs the primary and secondary screens described in this work will yield a variety of active, bioavailable, and synthetically amenable lead compounds to further build on this technology.
But the country is volatile and that could change soon, especially if Georgia faces a tough winter plagued by power cuts and a post-war economic crisis.Alex Rondeli, a veteran foreign-policy analyst, believes that when the time is right the Russians may well unearth someone more amenable to lead Georgia.
Initial SAR studies indicated that these novel series of integrase inhibitors are amenable to lead optimization.
A series of pyrazolo-pyrido-diazepine dione analogs demonstrated to be particularly amenable to lead optimization through a couple of cycles in order to improve specificity for isoforms Nox4 and Nox1 and had excellent pharmacokinetic parameters by oral route.
Davies is amenable to reprising the lead role in future, stating: "If David writes more, I'm happy to do them.
Analysis of the structural aspects of cellular CDKIs leads to the identification of inhibitory lead peptides amenable to peptidomimetic development.
The 2935 (94%, Dataset S9) that were amenable to ET analysis lead to 258 enzymatic annotations, as shown in Table 7.
One can easily imagine that this arrangement of adjacent subpockets makes this type of PPI particularly amenable to fragment-based lead (or drug) discovery (FBLD or FBDD) strategies.
An unbiased gene expression analysis coupled with a design amenable to refined statistics led us to identify a connection between mTORC1 and V-ATPase genes.
But that very process — of discussion and questions aimed at a deeper understanding — also led to the amenable conclusion of the mandate in April, she said.
Restricting the explored chemical space to those compounds amenable to chemical synthesis does not lead to a significant increase in computational demands.
