The phrase "amelioration target" is correct and usable in written English.
It can be used in contexts related to goals or objectives aimed at improving a situation or condition.
Example: "Our team has set an amelioration target to reduce waste by 30% over the next year."
Alternatives: "improvement goal" or "enhancement objective".
The differential regulation of osteoclastogenesis by Notch2/Dll1 and Notch1/Jagged1 axes may be a novel target for amelioration of bone erosion in RA patients.
Low dose of MG132 could reverse these changes and improve renal injury, and maybe it is a potent target for amelioration of DN patient.
They proffered the modulation of autophagy as a promising future clinical target in the amelioration of neurodegenerative disorders [ 46].
In conclusion, the results of this study validate AMP deaminase as potential new drug target for the amelioration of insulin resistance, which is one of the underlying causes of the metabolic syndrome and Type II diabetes.
We provide novel evidence for the implication of miR-33a, a SREBP-2 intronic miRNA, in OA pathogenesis, identifying it as a dual regulator of cholesterol synthesis and cholesterol efflux-related genes in OA chondrocytes, suggesting its potential use as a novel target for the amelioration of the OA phenotype.
Analysis of this mechanism could lead to the identification of novel therapeutic targets for the amelioration of age-related disorders and extension of healthspan.
Elucidation of the pathways linking changes in brain plasticity to behavior hopefully also will point out potential new targets for the amelioration, reversal, or prevention of alcohol-induced changes in brain circuitry.
MKK7 overexpression by cDNA transfection abrogated myricetin-reduced apoptosis-related protein expression, confirming that the MKK7/JNK signal pathway is the key target for myricetin-induced amelioration.
This review provides a landscape of central arterial aging and age-disease interactions, integrating perspectives that range from humans to molecules, with the goal that future therapies for cardiovascular diseases, such as hypertension, also will target the prevention or amelioration of unsuccessful arterial aging.
Pharmacological blockade of islet NO production by the NOS inhibitor NG-nitro-L-arginine methyl ester (L-NAME) greatly improved hormone secretion from GK islets suggesting islet NOS activity being an important target to inactivate for amelioration of islet cell function.
