According to the dopamine aging hypothesis, an amelioration of processing inefficiency of older adults under dopaminergic stimulation (Bromocriptine) was expected, and thus an attenuation of the differences from the young.
"Our data do not support previous hypotheses, which suggested that climatic amelioration and a lengthy period of human adaptation were necessary for successful human colonization of the high Andes," the study authors wrote.
Whereas these immunological changes may lead to an amelioration of existing RA symptoms, our study raises the hypothesis that they may also protect from clinical onset.
The reviewer highlights several misleading statements in the manuscript, specifically pointing out that: i) The amelioration of mutational damage through the bottleneck is a hypothesis; ii) Not all oocytes have heteroplasmy; iii) Discrete models of mtDNA populations do exist; iv) Statistical analyses of bottleneck mechanisms do exist.
We tested the hypothesis that improvements in metabolic hormones are associated with amelioration of pulmonary hemodynamics in a 48-year-old morbidly obese female IPAH patient who underwent bariatric surgery.
This study supports the hypothesis that NMDA receptor activation is injurious during focal ischemia and that amelioration of focal ischemic brain damage by NMDA receptor antagonists persists under normothermic conditions.
In the light of the relatively small numbers of patients in each genotype group, however, our data should be regarded as an interesting new hypothesis possibly adding to the elucidation of the multifactorial mechanisms underlying pregnancy-induced amelioration and the postpartum flare, but the data do not necessarily prove the genetic association.
These findings indicate that other mechanisms such as activation of paracrine pathways may play an important role on cardiac performance amelioration at week 2 [1], but additional studies will be needed in the future to test this hypothesis.
The amelioration of FMD was correlated with reduced arterial stiffness and decreasing CP height and support the hypothesis that restoration of endothelial function is closely related to atherosclerotic regression.
This study supports the hypothesis that N-methyl-D-aspartate receptor activation is injurious during focal ischemia and that amelioration of focal ischemic brain damage by N-methyl-D-aspartate receptor antagonists persists under normothermic conditions.
The neurotrophic hypothesis of depression states that the major depressive episode is associated with lower neurotrophic factors levels, which increase with amelioration of depressive symptoms.
