Sentence examples for ameliorating the underlying from inspiring English sources

However, in view of recent advances underlining the essential role of p38 MAPK in IL-10 expression and in Th2 cell functions and of the regulatory capacities of IL-10 and Th2 cells in Th1-driven inflammation, p38 MAPK inhibitors might be associated with some unwanted effects on the immune system, enhancing rather than ameliorating the underlying inflammatory response in Th1-driven diseases.

But venting to anonymous colleagues is about the least effective approach to ameliorating the underlying conditions making workers unhappy in the workforce.

Mechanical ventilation can no longer be viewed simply as a harmless support modality that is employed to keep patients alive while disease-specific treatments are used to ameliorate the underlying pathology.

Our finding that psychopathology is not mediated by the children's intellectual impairment does not support the use of cognitive remediation for ameliorating the mechanisms underlying psychopathology in children with 22q11.2DS.

These oligonucleotides are designed to repair genetic mutations, to modify genomic sequences in order to compensate for gene deletions, or to modify RNA processing in order to ameliorate the effects of the underlying gene mutation.

Since primary dystonia seems to result from a chronic cellular dysfunction, rather than a degenerative process, there are greater grounds for the belief that it may eventually be possible to ameliorate the disease by correcting the underlying dysfunction in these pathways.

Based on results from a large number of experimental studies on diabetes and obesity, ameliorating the above-mentioned nutrient pathways could be a mechanism underlying dietary restriction-mediated improvement of obesity and diabetes.

For example, digoxin is often highly effective in ameliorating the symptoms of congestive heart failure (mechanism) but does nothing to modify the underlying coronary artery disease (cause).

Herein, we describe the scientific and therapeutic rationale underlying efforts utilizing umbilical cord blood (UCB) as a therapy for ameliorating the progression of this autoimmune disease.

Current treatment options for AD are still limited to acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine), NMDA (N-methyl-D-aspartate) receptor antagonists (memantine) or other supportive strategies ameliorating the symptoms, rather than treating the underlying causes of neurodegeneration [ 2].

Ameliorating the neurocognitive and physical deficits that accompany traumatic brain injury would be of substantial benefit, but the mechanisms that underlie them are poorly characterized.