They sometimes combine different therapeutic approaches based on different theoretical models, everybody with the same aim to ameliorate functionality, participation and well-being of PwMS.
Potentially enhancing premotor functionality in Dbx1-derived neurons could ameliorate obstructive sleep apnea.
Through a variety of mechanisms, therapeutic lymphopenia appears to trigger homeostatic processes that favor the proliferation and functionality of anti-tumor effector T-cells, while also ameliorating tumor-induced immunosuppression [ 42].
The tendency of non-disease genes to have closer paralogues than disease genes has previously been attributed to the fact that a close paralogue may be able to ameliorate the effect of a loss-of-function mutation in a gene by virtue of its similar functionality [ 16].
Strategies to ameliorate this issue have emerged, such as installation of planarity-breaking functionality, or attachment of hydrophilic functionality that does not directly engage with the target, but extends toward solvent.
The results suggest that NO probably ameliorates symptoms and other effects of Fe deficiency by improving the functionality of the small amounts of Fe present in Fe-deficient leaves.
Many have envisioned that the current void of therapies to ameliorate kidney disease could be filled at the level of restoring functionality to individual nephrons if endogenous renal stem cells were identified or if renal stem cells could be grown and manipulated in vitro.
Interestingly, although n-HA impeded proliferation during the culture period (days 1, 4 and 7), the cell functionality such as alkaline phosphatase (ALP) and protein expressions were ameliorated on mineralized nanofibers.
In fact, studies have successfully demonstrated neuroprotection against apoptosis via restoration of mitochondrial functionality by natural products, such as the herbal medicine Chunghyuldan, which ameliorated PD-like behavioral symptoms by preserving dopaminergic neurons in the nigrostriatal region of PD mice model [ 52].
The functionality of the TregPMA cells has been demonstrated in vivo by their potential to ameliorate the disease phenotype in a CD45RB transfer colitis mouse model.
