Sentence examples for ameliorated progression from inspiring English sources

Blockade of gelatinase activity using a small molecule inhibitor (BAY-12-9566) ameliorated progression of proteinuria and restored the architecture of the glomerular basement membrane in α1 integrin-null Alport mice, suggesting that elevated gelatinase activity exacerbates glomerular disease progression in these mice.

Morisaki and colleagues [ 11] found that starches (more so than Ringers lactate) ameliorated progression of microvascular and parenchymal injury during the development of peritonitis in sheep.

Importantly, overexpressing miR-22 ameliorated progression of GC in an established experimental xenograft model and repressed the peritoneal dissemination and distal pulmonary metastases in vivo.

During EAE, a higher number of infiltrated immune cells correlated with increased disease severity [ 33] and blockade of CCL2-CCR2 signamelioratedorated progression of EAE together with a decrease in the number of infiltrating immune cells [ 34].

The Primavera study is the first prospective, controlled trial to assess whether ESA treatment could ameliorate progression of chronic kidney disease (CKD) in non-anemic patients.

The challenge is therefore to find those generic anti-fibrotic strategies that have potential to ameliorate progression in multiple organs, that is, the overlap.

The database is expected to provide important long-term information on CKD progression, nutritional and metabolic derangements that accompany CKD progression and treatment strategies to ameliorate progression and complications of CKD.

These results may have relevant clinical implications, suggesting that therapies aimed to restore the autophagic flux at early stages of NAFLD, such as NAS, might ameliorate progression to more advanced and irreversible forms of liver disease, such as NASH.

Several important limitations included the lack of comparability in disease severity, inadequate sample size, insufficient suppression of inflammation, and possible differences in intake of non-steroidal anti-inflammatory agents (NSAIDs), which have been shown to ameliorate progression [ 5].

In addition, IFNT alters metabolic pathways in rats to mitigate against obesity and diabetes and these unpublished results provide the basis for future research to understand mechanisms whereby this novel interferon can be used therapeutically to prevent or ameliorate progression of inflammatory diseases.

Our results showed that CeCl3@mSiO2 efficiently ameliorated the progression of DC.