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This type of drug should aim at the host's immune response to alleviate the effects of influenza and also exhibit ameliorated efficacy and safety by targeting required cellular proteins for influenza virus replication [ 39– 41].
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Modification of HDL in diabetes by glycation and oxidation may ameliorate efficacy of its vasoprotective functions [ 13].
Technical aspects to ameliorate efficacy of delivery may further improve its impact on domain-specific cognitive abilities.
The possibility that quercetin may ameliorate efficacy of chemotherapy is strengthen by the safety of the molecule administered through intravenous infusion.
Nebulized antibiotics could be a promising alternative to ameliorate antibacterial efficacy.
These findings suggest that selective inhibition of the KGF/KGFR pathway may provide a useful tool to ameliorate the efficacy of the therapeutic strategies for certain epithelial tumors.
7, 47 Combining two agents with different mechanisms of action, may improve efficacy relative to single-agent therapy, and the use of memantine with oral ChEIs may ameliorate ChEI-related GI AEs.
The utility of any animal model to serve as a screen for novel treatments is considered related to the extent to which the schizophrenia-relevant behaviors it exhibits can be ameliorated by drugs with known efficacy in schizophrenia but not by drugs known to be therapeutic for brain disorders other than schizophrenia.
Several attempts have therefore been made to further develop ancillary drug with the aim to preserve the high therapeutic activity of CDDP by reducing the undesired side-effects, such as sunitinib, which could improve chemotherapeutic efficacy and ameliorate CDDP-induced nephrotoxicity in experimental animals [ 13].
Mexiletine (10 100 mg/kg, p.o)., a sodium channel blocker, dose-dependently ameliorated mechanical allodynia in rats treated at 3 weeks; however, the efficacy was diminished at 7 weeks.
We next aimed to elucidate if ameliorated fibrosis observed upon Hydralazine treatment was due to its de-methylating efficacy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com