Sentence examples for ameliorated development from inspiring English sources

Genetic deficiency of Ar significantly ameliorated development of key endpoints linked with early diabetic nephropathy in vivo.

In contrast, treatment with anti-CD40L antibodies prior to CIA induction ameliorated development of disease [ 80], resulting in less synovial inflammation, and less bone erosion [ 81].

We demonstrate that donor-like MHC class I protein therapy induces population of CD4+CD25+CD8−FoxP3+ cells with potential to ameliorate development of transplant vascular disease and evoke CD4+ positive FoxP3 negative mast cells in the secondary hosts.

Antiepileptic drugs (AEDs) ameliorate development of this behavioral abnormality.

Development of novel methodologies to control the anti-donor T cell response elicited through the indirect pathway represent an effective strategy to ameliorate development of CAV and CR, the major obstacles to the long-term success of solid organ transplantation that the currently employed immunosuppressive drugs fail to prevent.

These data clearly demonstrated the unique capacity of the probiotic strains, in particular L. paracasei DSM 13434 and L. plantarum DSM 15312 to ameliorate development of chronic EAE and a direct correlation in their ability to suppress the disease-inducing inflammatory T cells.

The purpose of study was to determine whether prolonged administration of co-ultramicronized PEA + luteolin (PEA-LUT) would ameliorate development of arthritis by using a CIA model.

Several studies have reported that MSCs can ameliorate development of EAE through suppression of T cell-mediated responses., In the present study, we administered shBecn1-MSCs as a treatment of EAE and we found that these MSCs ameliorate the severity of EAE more efficiently than control MSCs.

Experimental colitis in rats resulted in elevated circulating leptin levels which correlate with the degree of inflammation and the development of anorexia [ 77] and leptin antagonist ameliorated the development of chronic experimental colitis [ 78].

Furthermore, 5b could significantly suppress the progression of carrageenan-induced hind paw edema compared to indomethacin at a dosage of 10 mg/kg/day, and dose-dependently ameliorated the development of adjuvant-induced arthritis (AIA) validated by arthritic scores and H&E staining of joints.

Fig. 2B shows that CD28SA application ameliorated disease development in both, a prophylactic and a therapeutic setting.