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To ameliorate inflammation, clinical trials abound that focus on COX-2 inhibition.
Current treatment strategy provides strong potential for further development of a gene therapeutic system to ameliorate inflammation and progressive atherosclerotic plaques.
In several models, vagus nerve activation with the α7 nicotinic acetylcholine receptor (α7-nAChR) agonists has been demonstrated to ameliorate inflammation.
And a contradictory role of galectin-4 on intestinal inflammation was stated to exacerbate (Hokama et al., 2004; Hokama et al., 2008) or ameliorate inflammation (Paclik et al., 2008a).
As a consequence of their physiologic functions, SP-A and SP-D-dependent pathways are targets for clinical therapies designed to limit the proliferation of microoorgansims and to ameliorate inflammation following pulmonary infection.
In conclusion, low-protein diet supplemented with keto-amino acids contribute to ameliorate inflammation in the progression of type 2 diabetic nephropathy through regulating inflammatory factors production, including TNF-α, CRP and adiponectin.
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Our results showed that Ang-1 treatment could ameliorate inflammation-induced leakage, inhibit inflammatory cell infiltration into the brain and spinal cord, and improve functional impairment associated with EAE in a dose-dependent manner.
Statins reduce cardiovascular risks by improving hypercholesterolemia, reducing vascular smooth muscle proliferation, and ameliorating inflammation.
Open image in new window Figure 3 The different molecular mechanism of galectin-4 in exacerbating or ameliorating inflammation.
Our results showed that PDI was significantly more effective than MIC in ameliorating inflammation after 15 days.
Indeed inhibition of GSK3β or ablation of the GSK3β gene ameliorates inflammation dependent arthritis [29].
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