Sentence examples for ameliorate defects from inspiring English sources

In contrast, injection of wnt-5 RNA cannot ameliorate defects in fz-2 morphant embryos (Fig. 8E).

Assessment of 13-day-old Tk2 −/− mice treated with dCMP+dTMP 200 mg/kg/day each (Tk2 −/− 200dCMP/dTMP) demonstrated that in mutant animals, the compounds raise dTTP concentrations, increase levels of mtDNA, ameliorate defects of mitochondrial respiratory chain enzymes, and significantly prolong their lifespan (34 days with treatment versus 13 days untreated).

Given that forced expression of LARGE in cells led to a significant increase in the ability of α-dystroglycan to bind its ligands, and even ameliorated defects in receptor function of the α-dystroglycan produced by fibroblasts from dystroglycanopathy patients, this enzyme has received a great deal of attention.

Such an understanding may also help ameliorate immunological defects in aging.

Ginkgo biloba extract (EGb 761) has been shown to ameliorate some defects associated with the insulin resistance syndrome and so patients with Type 2 diabetes mellitus (T2DM) may be inclined to co-ingest the herb with their medications, such as metformin.

The mt-sAC pathway opens a new window of opportunity to ameliorate mitochondrial defects.

Furthermore, we show that the administration of TSA on SMA model mice can ameliorate the defects in muscle development observed.

Thus, an ideal therapeutic agent should ameliorate the defects arising from PPT1 deficiency as well as oxidative stress.

As shown in Figure 1 figure supplement 1B, ectopic expression of LAP2α did not ameliorate nuclear defects in HGPS cells.

By modulating eIF2B function, ISRIB promises to be an invaluable tool in proof-of-principle studies aiming to ameliorate cognitive defects resulting from neurodegenerative diseases.

Blockade of SGLT2 also appears to ameliorate pathophysiological defects underlying T2DM other than hyperglycemia, including factors such as weight gain, blood pressure, and lipids.