Exact(14)
It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
By applying western blot, it was found that hr5F alleviates the high glucose-induced superoxide overproduction insults by regulating SIRT1-PGC-1α/Nrf2 pathway, together with regulating NRF-1, mtTFA, Bax/Bcl-2 to ameliorate cell apoptosis.
Depending on the stressor and cell type, TG2 can either facilitate or ameliorate cell death processes [12], [18], [22], [23], [24], [25], [26], [27].
These findings suggest that the cellular localization of TG2 may be important in determining whether TG2 will facilitate or ameliorate cell death processes, particularly in response to OGD.
Caspase inhibitor, z-VAD-FMK, could significantly ameliorate cell death induced by celastrol.
We next examined whether supplement of DM‐OG could ameliorate cell death caused by Gln withdrawal and L‐ASNase treatment.
Similar(46)
A limited number of studies investigating the influence of nutritional state and some micronutrients on cell-mediated immunity and early enteral nutrition have been shown to ameliorate cell-mediated immunity in ICU patients [ 34, 35].
According to these results, BG-Sr ameliorated cell proliferation and developed an antioxidative defense against ROS.
Third, removal of Fenton reactants using a mitochondrial permeable iron chelator and catalase ameliorated cell death.
In contrast, if the stressor did not result in increased transamidating activity, TG2 ameliorated cell death [29].
Inhibition of JNK, p38 and ERK/MAPK pathway by their respective inhibitors ameliorated cell toxicity induced by cocaine and gp120.
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