Exact(5)
Indeed, cationic antibiotics that broadly inhibit such channels, such as streptomycin, were shown to ameliorate aspects of muscle disease in mdx mice.
There has been enormous enthusiasm about the potential to intervene in and ameliorate aspects of this documented spectrum of disability both during and after the ICU stay.
Together these models provide compelling evidence for targeted therapeutic inhibition of the 11β-HSD1 enzyme as a means to ameliorate aspects of the metabolic syndrome in humans.
We additionally determined the ability of pyridostigmine, an acetylcholinesterase inhibitor, to ameliorate aspects of the behavioral phenotype related to NMJ dysfunction.
The authors also speculate that KU-32 may have the potential to ameliorate aspects of painful diabetic neuropathy and indeed induction of HSP70 has previously been shown to ameliorate allodynia in a model of neuropathic pain induced by physical nerve injury (Kalmar et al., 2003).
Similar(55)
Are there things you can do to eliminate or ameliorate the aspects of the job that bug you?
Radiesse can provide volume augmentation to ameliorate this aspect.
Unlike Casp8 heterozygosity, Ripk3 and Mlkl deletion ameliorated many aspects of the systemic cpdm phenotype.
In MRL lpr mice a truncated fractalkine analogue with the capability of antagonizing the actions of fractalkine also significantly ameliorated several aspects of lupus nephritis and vasculitis [ 9].
It is not surprising, therefore, that full D2 receptor agonists have proven effective in reducing blood pressure and plasma glucose and lipids, thereby ameliorating some aspects of metabolic syndrome [ 68, 71, 72].
Therefore, relatively low doses of KO to Zucker rats, which was previously shown to downregulate peripheral endocannabinoid levels, ameliorating some aspects of the metabolic syndrome [ 49], in the brain reduces only 2-AG levels, suggesting that the beneficial effect of KO on the metabolic syndrome is mostly exerted by modifying endocannabinoid levels in peripheral tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com