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Our hash tables stored odd-length k-mers so that reverse-complementary sequences can be combined without the ambiguous orientation of palindromic sequences (e.g., ATCGAT).
One probe for annotated transcripts with known orientation was designed to construct a high-density oligo-DNA microarray, while two probes with both orientations were designed for contigs with ambiguous orientation (see Table 1).
Although existing bioinformatics tools can recognize CRISPR loci by their characteristic repeat-spacer architecture, they generally output CRISPR arrays of ambiguous orientation and thus do not determine the strand from which crRNAs are processed.
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His books were out of print, his marriage on the verge of collapse and his ambiguous sexual orientation a daily torment.
They have, of course, produced a steady supply of scandalous scuttlebutt, including an alcoholic leader, who was forced to resign in January, and two leadership candidates of ambiguous sexual orientation.
The idea for Smithers' ambiguous sexual orientation came from Sam Simon, who proposed that Smithers should be gay, but little attention should be drawn to it.
Over his decades in the spotlight, however, Bowie's gender fluidity and ambiguous sexual orientation prompted questions and confusion -- especially in the U.S., as the singer once told Blender magazine.
Necker cubes are orthographically projected wire cubes that are inherently ambiguous in orientation (Fig. 1A).
This is where the reality TV golden ratio comes into play, as the selected contestants also happen to be charismatic and extremely attractive with ambiguous sexual orientations and a touch of gentle stereotype fulfillment (i.e. breakdancers from the inner city), leaving room for a variety of PG-rated narratives as expressed in short video cuts between performances.
When predictions had ambiguous strand orientations, e.g. occurred in a genome location that could be transcribed from either strand, the program RNAstrand [ 115] was used to determine if structure was more likely to be in the forward or reverse strand.
We found that judgments of a perceptually ambiguous social category, sexual orientation, varied as a function of a perceptually obvious social category, race.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com