The phrase "alzheimer case" is not entirely correct in written English; it should be "Alzheimer's case" to reflect proper possessive form.
You can use it when discussing a specific instance or situation involving a person diagnosed with Alzheimer's disease.
Example: "The Alzheimer's case presented unique challenges for the caregivers involved."
Alternatives: "case of Alzheimer's" or "Alzheimer's patient case".
A defect in the gene that directs production of apolipoprotein E (ApoE), which is involved in cholesterol transport, may be a factor in the majority of late-onset Alzheimer cases.
However, such mutations only account for a very small percentage of Alzheimer cases.
In a study of 18 Alzheimer cases and 19 controls there was a statistically significant difference reported for the T10652 expected reference signal (p<0.05), although it was not specified if it was the C allele substitution [65].
One locus (S100A2), which is methylated in neurons (Fig. 5C) was significantly less methylated in the DNA from Alzheimer cases compared to age-matched controls (Fig. 3), possibly due to large-scale loss of neurons associated with that disease.
Extensive experiments on two genome-wide SNP data sets (Parkinson case-control data comprised of 408,803 SNPs and Alzheimer case-control data comprised of 380,157 SNPs) and 10 gene data sets have demonstrated that the proposed model significantly reduced prediction errors and outperformed most existing the-state-of-the-art random forests.
We conduct a series of experiments on two genome-wide SNP data sets (Parkinson disease case-control data set comprised of 408, 803 SNPs and Alzheimer case-control data set comprised of 380, 157 SNPs) to demonstrate the effectiveness of the proposed RF method.
A very recent work showed through meta-analysis of genome-wide association studies involving 2540 Alzheimer cases that changes in glutamate metabolism are overrepresented in data from patients with AD [ 39].
Diagnostic accuracy of individual instruments and incremental value of entorhinal cortex volume on MRI and p-τ/Aβ ration in CSF after administration of Rey's Auditory Verbal Learning Memory Test are calculated and expressed as the 'Net Reclassification Improvement' (NRI), which is the change in the percentage of individuals that are correctly diagnosed as Alzheimer or non-Alzheimer case.
"One of my jobs was to make sure the Alzheimer's cases really were cases — that they had used some reasonable criteria" for diagnosis, Dr. Mayeux said.
** the 1000/100 ratio is made up for ease of calculation, the real ratio will depend on the population you test, though it looks like it the Alzheimer's case these numbers aren't far off.
