The phrase "altogether abnormal" is correct and usable in written English.
It can be used to describe something that is completely or entirely unusual or out of the ordinary.
Example: "The results of the experiment were altogether abnormal, leading the researchers to question their methodology."
Alternatives: "completely unusual" or "entirely atypical".
Altogether, the abnormal surrounding stroma suggests that a differentiation defect might have occurred during development, resulting in the formation of epithelia expressing aberrant transcription factors.
Altogether, these results demonstrate that abnormal, unliganded opsin signaling activity induces photoreceptor apoptosis in Rpe65-mediated LCA disease triggered by Bcl-2-related apoptotic pathway.
These findings altogether support the assumption of abnormal axonal milieu and myelin structures in schizophrenia.
Altogether, the accumulation of morphologically abnormal tubule cells and concomitant loss of luminal connectivity present striking morphological parallels to the NPHP loss-of-function phenotype in humans, suggesting that planarian protonephridia can develop cyst-like structures.
Altogether, our results on the abnormal baseline expression of Jagged/Notch molecules and these atypical signalling signatures suggest that the Jagged/Notch pathway may be involved in the pathogenesis of RA.
Altogether, more than 80% EGFP-Hec1 prometaphases were abnormal and disorganized multipolar prometaphases were the predominant phenotype (Figure 1E, lower graph).
Altogether, these findings suggest a possible link between abnormal lipid metabolism and connective tissue in OA.
Paper, even typed printouts, are also more prone to human error: one obstetrician grabbed the wrong sheet off the pile and consulted with me about my "normal" blood results – it was only when I got home I realised we'd been looking at another patient's printout altogether (and it turned out my own had an abnormal result that needed follow-up).
Altogether, these data suggest that diacerein/rhein could impact the abnormal subchondral bone metabolism in OA by reducing the synthesis of resorptive factors and osteoclast formation.
After this initial enamel layer is laid down, the ameloblasts become disorganized and any enamel elaborated after this point is abnormal, with reduced rod density, or is absent altogether.
