Although worsening renal function was associated with a negative prognosis, the mortality benefit of spironolactone was still demonstrable.
Although worsening or newly appearing grades 3 and 4 AEs were minimal after 2 and 4 years of treatment with imatinib, 4% of patients discontinued therapy because of an AE by the 5-year follow-up.
Although worsening of symptoms was independently associated with progression of carcinoid heart disease, (OR 99, 95% CI 17 573, P<0.001, Table 3) the wide confidence interval implies some uncertainty in this estimate.
7 Although worsening oxygenation is a risk factor for ARDS mortality, patients generally die from multisystem organ failure or progressive underlying illness; only a minority of ARDS patients (13%19%%) die from refractory respiratory failure.
First, a carryover effect of previous immunosuppressive therapy cannot be ruled out, although worsening occurred in patients who had received an immunosuppressive therapeutic regimen like that of improved/stabilized patients.
In adults with septic shock, higher doses of NE increase PVR/SVR, although without worsening RV performance [ 105].
Since July 2009, the date of these accounts, Liverpool's position can be assumed to have worsened, although commercial deals, including sponsorships, have improved.
The initial lesions identified on Schumacher's brain have not worsened, although doctors did confirm that more were discovered and there are still "many haematomas in the brain".
Russian officials have sought to distance themselves from Mr. Assad in recent weeks as the nearly two-year conflict in Syria has worsened, although they still strongly oppose military intervention in favor of a negotiated transition.
The situation worsened, although it was not disastrous until after the collapse of France.
The initial damage assessment was that little harm had been done, although vibrations had worsened, but this was incorrect as the damage to the hull structure and plating proved to be extensive.
