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The phrase "although we know that" is correct and usable in written English.
It can be used to introduce a contrast or concession in a statement, acknowledging a fact while presenting a differing viewpoint or situation.
Example: "Although we know that the project is challenging, we are committed to seeing it through to completion."
Alternatives: "even though we are aware that" or "despite knowing that".
Exact(60)
Although we know that polymerase chain reaction (PCR) is the method with the best sensitivity for HPV detection, we began this research looking for koilocytosis, which is highly suggestive of HPV infection.
Although we know that miR-122 is highly abundant in bulk liver samples, the expression of miR-122 may vary between hepatocytes and this would give some mutants a replicative advantage.
Although we know that soon there will be another one.
But although we know that wildfire is for the most part natural and impossible to suppress, we seem incapable of disengaging from our war against it.
Although we know that separation often means longer term happiness when relationships break down, there's no clear end goal for our love lives.
Thus, vitamins may be seen as good things, although we know that overdosing can kill.
For example, although we know that accumulation of senile plaques in which the β amyloid protein is the major component underlies both sporadic and familial Alzheimer disease, we have little knowledge on the molecular etiologies of sporadic Alzheimer disease.
Second, although we know that children experience between three and six respiratory tract infections per annum [ 2], we were unable to find evidence of the mean number of episodes of cough for which a child consults each year.
Although we know that his downfall is inevitable, it moves us just the same.
So although we know that certain practices should be done, it's very rarely that we go and really self-evaluate: What are we doing?
Although we know that bodily fluids are contagious, we still don't have a definitive picture of how the virus enters the body's cells.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com