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Peptides derived from BACE1 were found to be elevated in the media of cells expressing the protease, although we determined that BACE1 cannot shed itself (see below).
Although we determined that LCN7 promotes endothelial cell invasion, sprouting and angiogenesis in vivo, there remain a significant number of questions that remain to be addressed regarding the biological function of LCN7.
Although we determined that only official gene symbols should be accommodated in the tool, later versions can be updated with such functions, if there are user demands.
Although we determined that one major socioeconomic factor (number of bedrooms) was similar between cases and controls, there were significant differences in some demographic and socioeconomic variables between the two study groups, which could potentially affect effectiveness of the vaccine.
Although we determined that adenine propenal can also form oxopropenylated cysteine, searching for adducts on cysteine residues within HSA did not result in the identification of any modified sites.
Although we determined that some small-volume tumors showed a high degree of intratumoral metabolic heterogeneity, no one with stage T1 tumors died; therefore we could not perform subgroup analysis with stage T1 breast cancer patients.
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"Having considered the evidence, we determined that although it could be shown that the officer owed Mr Pimlott a duty of care, there is insufficient evidence that the duty was breached.
We determined that although these tubes have a relatively large thickness eccentricity (±4% of the nominal thickness), this had no effect on the recorded results.
We determined that although the atomic fluorescence detector was fundamentally linear down to at least 1 pg, the default peak integration scheme appeared to be optimized for > 10 15 pg cycle−1 and so could introduce non-linearity in smaller peaks (i.e. lower mass loadings).
We determined that although developed the same magnitude of temporary threshold shifts and hair cell loss, the d-galactose treated rats with increased CD in the inner ear exhibited a longer hearing recovery process and experienced higher permanent hearing threshold shifts at high frequencies than the saline-treated control rats.
For example, we determined that although the total 18O composition of our synthesized compounds matched the predicted amount, the 18O composition of the individual species differed, indicating that the assumptions of either complete, or no P-O bond-breakage in POCl3 were not met.
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