TL1A-S induces a Th1 response, although the functional significance of membrane-bound TL1A (TL1A-M) remains unknown.
However, spliced XBP1 might be play a minimal role in palmitic acid-induced inhibition of IL-4 and IFN-γ production by iNKT cells, although the functional role of spliced XBP1 in iNKT cells remains unknown.
Although the functional significance of anterior cingulate involvement in OCD remains unknown, electrophysiological evidence has linked this region to error-processing abnormalities in patients with OCD.
Although the functional effects of cholinergic activation have been extensively studied in pyramidal neurons within the hippocampus and entorhinal cortex, less is known about the role of cholinergic receptors on dentate gyrus neurons.
Although the functional repertoire of the three p53 family members shows considerable overlap, p63 and p73 have also distinct and unique biological functions.
Taken together, these experiments provide insight into the evolution of within-song type variation in song sparrows, although the functional significance of this level of variation and learning preferences based on variation remain enigmatic.
Although the functional receptors for TcdA and TcdB have not been definitely identified, both toxins seem to have different receptors.
Although the functional imaging techniques used in this study are noninvasive, the chimpanzees were anesthetized for imaging.
The extracellular domain (ECD) undergoes proteolytic cleavage by serine proteases, although the functional significance of this remains unknown.
We originally demonstrated expression of multiple isoforms of Abi1 [21], although the functional significance of the various isoforms has not been addressed.
Although the functional involvement of many transcription factors in keratinocyte differentiation has been known, however, it is not sufficient to understand the sophisticated regulatory mechanism underlying this process.
