Sentence examples for although pivotal from inspiring English sources

Although pivotal clinical trials are still ongoing, sufficient progress has been made to make relevant the question of the role of a malaria vaccine.

In addition, although pivotal for proper error-correction and SAC function, preliminary analyses hinted at a high degree of variation in KNL1 repeat evolution (Vleugel et al. 2012, 2013).

Although pivotal roles for colonic PGs and PTGS have been well-established in colorectal tumorigenesis (Castellone et al., 2005, Chulada et al., 2000, Oshima et al., 1996, Sonoshita et al., 2001), the profiles of circulating PG biosynthesis in CRC remain unclear.

Holocene climates and human impact in the Mediterranean basin have received much attention, but the Maltese Islands in the Central Mediterranean, although a pivotal area, have been little researched.

Although its pivotal secret won't pass any great scrutiny, the horror-thriller "Jessabelle," not to be confused with the recent shocker "Annabelle," is a watchably spooky concoction.

Although the pivotal role of STRA6 and LRAT in vitamin A uptake is widely recognized, the mechanisms that govern "buffering" of vitamin A within the eye still remain unknown.

Although a pivotal role of lipid-regulated TRPC channels in cardiac hypertrophic remodelling has repeatedly been demonstrated, their impact on contractility and excitability of the heart is still elusive.

Although the pivotal role of the CXCL12/CXCR4 axis in cell motility and consequently in cancer metastasis in several tissues is well established, the contribution of CXCL12 via its receptor CXCR7 is less understood.

Although the pivotal role of PRDM9 in defining the positions of individual recombination hotspots is established, a large number of potential PRDM9 binding sites in the genome are not being utilized.

Although many pivotal SNPs have been discovered, they are far less important to explaining the differences among populations, such as the differences in physical appearance, disease susceptibility [ 25], and drug responses [ 26].

Although the pivotal role of Klf5 in ESC self-renewal and ICM development has been at least in part elucidated, its mechanism of action and the genes that Klf5 controls are still not completely understood.