[Disclosure: I'm the co-author of a book about such a method, and chair of the board of a nonprofit that disseminates it.] So can tutoring, although it's hard to provide that on a large scale.
This had never been done before on a large scale.
Killer whales have at one time or another been targets of both commercial and subsistence whalers, although never on a large scale.
9 10 11 Although not previously recommended on a large scale, vaccination against influenza during the second and third pregnancy trimester was deemed an appropriate intervention to prevent maternal morbidity and mortality and to reduce the risk of adverse fetal outcomes.
Only coal plants with carbon capture and storage will, in effect, be allowed, although this technology is unproven on a large scale.
However, evaluating the performance of a method against a reference method that, although it is still used on a large scale, is widely recognized to be insufficiently sensitive is arguable.
RNA integrity is maintained with the immediate postcollection addition of commercially available inhibitors of RNAse enzymes such as RNAlater® or PAXgene tubes®, although these can be costly on a large scale (26).
Although this research was not always on a large scale or sophisticated by modern standards, it did aim to produce causal estimates.
Although the poverty level is improving on a large scale, these social dilemmas, including job scarcity and rural underdevelopment, continue to affect pockets of the population in visceral ways.
More work is necessary to find better methods for the conversion step, biomass to methane, on a large scale, although the bench-scale work already done indicates that net energy can result from bioconversion, with good yields of methane.
Growing preclinical and clinical evidence about blastocyst biopsy accuracy, safety and effectiveness indicate trophectoderm analysis as the most advantageous stage for all applications of preimplantation genetics although it was only recently introduced on a large scale into the clinical practice of IVF (Yang et al, 2012; Chang et al., 2013; Forman et al., 2013a, b; Scott et al., 2013a, b).
