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Although major progress has been made using mouse models to examine the disease progression (7– 10), our understanding is currently restricted by a lack of knowledge about the functions of, and even the precise location of, the CLN3 protein within cells.
Although major progress has been made in the last few years, the aetiology, pathogenesis, and progression of this disease are not fully understood.
Although major progress has been made in understanding of the pathophysiology of this injury, this has not yet led to substantial improvements in outcome.
Although major progress has been made in the design and selection of intrabodies, new developments and advances are needed to allow their efficient delivery and expression for treatment of human diseases.
Although major progress has been made in the basic research of leptospirosis, the pathogenesis remains to be elucidated [ 4- 6].
4,9,10 Although major progress has been achieved on the molecular basis for host-virus interactions, there is still limited understanding of this dynamic at the macroscale.
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Although major progresses have been recorded in recent years in the knowledge of the complex signaling pathways involved in ovarian carcinogenesis [ 2], the deciphering of its pathogenic journey is far from being complete.
But major progress has been made since then.
Major progress has been made, but techniques still have not been reduced to standard design practice.
In recent years, major progress has been made in understanding how (alternative) splicing is regulated.
Over the past several years, major progress has been made in generating irreversible inhibitors targeting the PADs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com