The phrase "although its importance" is correct and usable in written English.
It can be used to introduce a contrast or exception regarding the significance of a subject being discussed.
Example: "Although its importance cannot be overstated, the project faced numerous challenges that hindered its progress."
Alternatives: "despite its significance" or "even though it is important".
Therefore, its deletion may have an important role in the mental retardation observed in our patient, and although its importance is difficult to assess, as in the patients described by Pohjola et al., [ 26] and Couco et al., [ 27] in whom these genes are lost, some of them have a borderline development, learning disabilities or are apparently normal.
Although its importance was not realized at the time, this happenstance provided the basis for changing light into an electric signal.
The closing of the Suez Canal from 1967 to 1975 decreased shipping traffic in the gulf, although its importance grew during the Persian Gulf War (1990 91).
The knowledge and systematic application of the placebo effect remains limited, although its importance to the treatment of various medical conditions has increasingly been recognized.
Before World War II, Hohhot was still primarily a trading centre, although its importance had grown rapidly since the completion in 1922 of the railway linking it to Beijing and Tianjin to the southeast and Baotou to the west.
Other FGFs are glycosylated although its importance to function remains to be fully elucidated.
They did not want a draw, although that its importance was relative was perhaps revealed when Ronaldo was withdrawn after an hour.
Although its geopolitical importance is indisputable — it has about 80 million people, and the Suez Canal is an indispensable link in trade routes between Europe and Asia — its weight in the world economy is negligible.
Gout occurs less than would be expected and lower levels of uric acid have been found in people with MS. This has led to the theory that uric acid is protective, although its exact importance remains unknown.
Although its physiologic importance suggests a role in breast carcinogenesis, such activity has been controversial.
Although its physiological importance in non-nervous tissues has been confirmed by analysis of null mutation phenotypes, few endogenous editing substrates have been identified in numerous peripheral tissues and biological function of ADAR1 has not been fully understood.
