Present evidence indicates that the trivalent chromium compounds do not cause cancer although high concentrations in some in vitro systems have shown genetic toxicity.
Although high biomass concentration was obtained in culture of oxygen-tolerant Euhalothece sp., it is actually not practical to culture oxygen-sensitive algal strains if mixing is not sufficient.
Although high F− concentrations in groundwater were previously considered to be a problem mainly in hard rock areas, they have now been discovered in other environments as well (Chadha and Tamta 1999).
Although higher ATP concentrations (1.5 2 mM in Fig. 2a) and lower Mg2+ (2.5 mM in Fig. 1b) showed better dI repair activity, we decided using conventional human MMR reaction buffer containing 1 mM ATP and 5 mM Mg2+ for standard dI repair assay in order to compare dI correction versus human MMR activities described in the subsequent section.
The in vitro concentration of 8 μM AZT approximately corresponds to the pharmacological level utilized in ARV therapy in vivo, although higher concentrations of the drug were used as suprapharmacological concentrations.
Magnetite formation after reaction of Fe(II) with lepidocrocite has been observed previously [37], although high sulfate concentrations (not present in our study) may inhibit this process [2, 38].
Although, higher concentration of GSH was observed in case of indomethacin treatment; however, when the data was statistically analyzed, no significant difference was found compared to the arthritic control group (P < 0.19).
Although higher liver concentrations were initially observed in Abcb1a/1b−/− mice at 15 min, Act D liver concentrations decreased over the 6 h in all mice variants, and consequently no differences in AUC0 6 h were observed.
Although higher serum concentrations of trazodone were observed in patients with renal impairment, compared to those with normal renal function, these differences were not statistically significant [ 58].
In this study, although high concentrations of serum proteins in 100% serum can alter the osmolarity and pH of the preparation [ 17], very few patients had ocular discomfort which was tolerable.
