Although harm reduction practices can benefit some people, the biological vulnerabilities and heightened psychobiological responses to substance use among SMI clients tempers this conclusion (Mueser et al., 1998).
Although harm reduction strategies like clean needle exchanges and naloxone access laws have been widely adopted in recent years, no U.S. state has legally implemented a safe injection site, and law enforcement and neighborhood groups have opposed plans to start them. .
"High purity coke would obviously contain fewer contaminants and cutting agents," says Nutt, of the extra side effects such cutting agents could potentially have – though adds that, really, they're not the primary concern: "Although harm from cutting agents has certainly been documented in cocaine and other drugs – see PMA in ecstasy pills, for example – cocaine dosing is the main issue here".
It is likely that ENM use will become ever more commonplace in the future and provide many benefits, although harm from inadvertent human exposures may also increase.
Although harm was not demonstrated in the context of this experimental protocol, the significant changes to respiratory physiology caused by breathing through N95 mask materials raise the concern regarding prolonged use of N95-masks by pregnant healthcare workers.
Although it harms relatively few people, it can have life-altering consequences in those most severely affected.
But Brown's mistake – although it harms only his credibility, rather than his sales – was to suggest that conspiracies involve medieval sects gathering in the bowels of tourist locations to encourage misshapen thugs to go in search of mystical chalices or pyramids.
Although more harms recommendations were fulfilled in epoch 2 (m2 = 6.49, SD 2.66) than in epoch 1 (m1 = 5.39, SD 2.52; P = 0.04), only the recommendation to report harms per arm was satisfied by >90% of trials in epoch 2, whereas <60% reported withdrawals due to harms.
Harms data were under-evaluated within our evidence base, although unidentified harms could account for some studies' notable numbers of withdrawals or dropouts [ 40, 57, 65].
According to a press release in November 2008, although no harms were reported, the results were 'disappointing', not showing any significant differences between the two groups of participants.
