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The most primitive living vertebrates the jawless fishes (hagfish and lampreys)—do not have lymphoid tissues corresponding to a spleen or a thymus, and their immune responses, although demonstrable, are very weak and sluggish.
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Second, the differences in CFU observed at early times between TLR4 KO and WT mice, although statistically demonstrable display low significance and it is manifested at early times but not at later times [12], suggesting low influence of this TLR in the course of Brucella infection.
Although these demonstrable impacts are epidemiologically important, they also emphasise that OST on its own will be insufficient for controlling HIV within this population, with combined interventions including NSP, ART as well as ongoing sexual risk reduction most likely being needed.
Overall, it is found that the schemes' impacts both on the local communities and the environment are mostly marginally positive or neutral, although achieving clearly demonstrable benefits would require major upscaling of the effort involving broader changes than possible under this project.
Perhaps more important, 2 patients, aged 3.8 and 5.2 years, displayed no evidence of rickets in either wrist or knee films, although relatives exhibited demonstrable rachitic abnormalities.
Although there are demonstrable advantages to this approach to learning genetics, this unit is not "plug and play".
In summary, using eight different anti-Runx3 antibodies, in situ hybridization, TaqMan qRT-PCR, three different reporter mouse strains (Runx3-GFP-KI, R26-LacZ/Runx3Cre and R26-tdTomato/Runx3Cre) and rigorous re-analysis of the original Li-Runx3-LacZ mice, we are unable to demonstrate Runx3 expression in GIT epithelium although it is readily demonstrable in a series of adjacent tissues.
Well, admittedly, the Times said "demonstrable," not actually "demonstrated".
Crossing guards may have an overall positive effect on PMVCs, although this is not demonstrable without measurement of walking exposure.
Peak elastase concentrations were reduced in elafin-treated patients, although there was no demonstrable effect on peak myeloperoxidase concentrations.
In admixture, the 2 antibodies displayed synergism in their cytotoxicity although this was only demonstrable with defined ranges of antibody concentration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com