The phrase "alters the affinity" is correct and usable in written English.
It can be used in contexts related to chemistry, biology, or any field discussing interactions between substances or entities.
Example: "The introduction of the new compound alters the affinity of the enzyme for its substrate."
Alternatives: "changes the binding strength" or "modifies the attraction".
Because glycosylation alters the affinity of antibodies for Fc receptors, evidence suggests that glycosylation is a central mechanism for the immune system to tune a broad range of biological activities.
Amphotericin B alters the affinity and functional activity of the oligopeptide chemotactic factor receptor on human polymorphonuclear leukocytes.
It is known that α4β2 receptors are found at presynaptic terminals of dopaminergic neurons [74], suggesting that the CHRNA4 polymorphism alters the affinity of presynaptical nAChRs on dopaminergic neurons.
This is likely to reflect a structural change in the DR molecule which alters the affinity of binding of the DRβ chain specific monoclonal antibody while the DRα chain specific mAb remains unaffected.
We also observed an increase in Nkd1-β-catenin interaction in the presence of Wnt8 (Fig. 5B); however, it is unclear if this is a result of increased levels of cytoplasmic β-catenin due to excess Wnt8, or if Wnt signaling alters the affinity of Nkd1 for β-catenin, or both.
In mechanism #3, MK2 alters the affinity of p38 for ATP.
Thus, pharmacologic manipulation can alter the affinity of the chemotactic factor receptor on human PMN; this alteration is associated with a change in receptor function.
The results showed that the modification of the aptamer does not significantly alter the affinity of the aptamer for the antibiotic.
In vitro experiments also showed that artificial envelopment of Ad completely altered the affinity towards both human and murine red blood cells.
Furthermore, the cysteine at VL85 of ds-FV57 was mutated to serine to construct ds-FV57VL85Ser in order to avoid potential mis-formed disulfide bonds which would alter the affinity of the scFv.
By altering the affinity of the receptor using pharmacological means one may be able to modify the biological activity of human PMNs.
