Sentence examples for alters the accessibility from inspiring English sources

These observations suggest that association of MTAg with pp60c-src alters the accessibility of pp60c-src tyrosine residues for phosphorylation in vitro and increases pp60c-src protein kinase activity.

Interestingly, disrupting the epigenome alters the accessibility of linearly arranged Sox2 binding sites as well as the extent of 3D enhancer clustering.

DNA cytosine methylation alters the accessibility for transcription factor complexes at a local level and, as with histone modifications, affects chromatin structure at regional and genome-wide levels.

SmpB binding also alters the accessibility of the upstream sequence and pseudoknot 1 to nucleases in probing experiments, leading to the proposal that it plays a role in frame choice [ 36].

However, it is not clear, from the X-ray crystal structure of p110αH1047R in complex with the nSH2 and iSH2 domains of p85α (p85αnSH2−iSH2) [ 25], whether the H1047R mutation alters the accessibility of the putative lipid-binding surface of the C2 domain.

This packaging can be distorted by epigenetic alterations and may alter the accessibility of certain regions of the genome in cancer cells.

Hodges, H. C. et al. Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.

Such modifications alter the accessibility of the DNA to other proteins and thereby demarcate transcriptionally 'active' or 'repressed' chromatin regions.

We previously demonstrated that cocaine binding and dopamine transport alter the accessibility of Cys342 in the third intracellular loop (IL3).

The impregnation of MgO on mayenite increases the surface areas and pore volume (M3 and M4) but the increase of the pore diameter is smaller compared to the Li2O impregnation case, which may alter the accessibility to the active sites.

This finding confirmed the direct role of DNA methylation in altering the accessibility of transcription factors to the NR2B promoter.